![]() Many treatable health conditions (e.g., sleep disorders, hypertension, diabetes, heart failure, hypothyroid), deficiencies (e.g., vitamin B12, tryptophan), as well as lack of movement and social interactions can affect memory and thinking. BOCA is available online gratis at Peer Review reports BOCA has the potential to reduce the cost and improve the quality of longitudinal cognitive tracking essential for testing novel interventions designed to reduce or reverse cognitive aging. The effect of the screen size tested by BOCA administration on a large computer screen and re-administration of the BOCA to the same participant on a smartphone was insignificant (β = 0.82, p = 0.17 positive β indicates greater score on a smartphone). The practice effect tested by daily BOCA administration over 10 days was insignificant (β = 0.03, p = 0.68). The study revealed strong ( R = 0.94, p < 0.001) test-retest reliability of the total BOCA score one week after participants’ initial administration. BOCA demonstrated strong correlation with Montreal Cognitive Assessment (MoCA) ( R = 0.90, p < 0.001). The Cronbach’s alpha was 0.87 implying good internal consistency. Test scores were significantly different between patients and controls ( p < 0.001) suggesting good discriminative ability. BOCA was administered to patients with cognitive impairment ( n = 50) and age- and education-matched controls ( n = 50). BOCA evaluates eight cognitive domains: 1) Memory/Immediate Recall, 2) Combinatorial Language Comprehension/Prefrontal Synthesis, 3) Visuospatial Reasoning/Mental rotation, 4) Executive function/Clock Test, 5) Attention, 6) Mental math, 7) Orientation, and 8) Memory/Delayed Recall. BOCA uses randomly selected non-repeating tasks to minimize practice effects. The goal of this project was to validate BOCA. We developed a self-administered 10-min at-home test intended for longitudinal cognitive monitoring, Boston Cognitive Assessment or BOCA. The MoCA is an acceptable cognitive screening test for the cognitive evaluation of FM patients.Longitudinal cognitive testing is essential for developing novel preventive interventions for dementia and Alzheimer’s disease however, the few available tools have significant practice effect and depend on an external evaluator. Moderate positive correlations were found between the MoCA and the computerised cognitive scores as follows: Global Cognitive Score (r=0.493**, p=0.00), Memory Index Score (r= 0.384**, p=0.002), Executive Function Index Score (r=0.461**, p=0.00), Attention Index Score (r=0.310*, p=0.016), Information Processing Speed Index Score (r=0.435**, p=0.001), and Motor Skills (r=0.406**, p=0.002). Patient effort was controlled on the TOMM (Test of Memory Malingering). ![]() FM symptoms were assessed on the Fibromyalgia Impact Questionnaire (FIQ), the Widespread Pain Index (WPI), the Symptom Severity Scale (SSS), and the Beck Depression Inventory (BDI-2). Sixty-two FM patients (55 women, 7 men, mean age = 46.17 years, sd=12.56) were administered the MoCA and a computerised cognitive assessment battery. The aim of this study is to examine whether the Montreal Cognitive Assessment (MoCA) test is a valid measure of cognitive assessment in FM patients, by comparing it to a comprehensive computerised cognitive assessment battery. This points to the need for a briefer valid evaluation tool for cognitive dysfunction in FM. However, recent studies have shown that there is no correlation between these subjective measures of cognitive dysfunction and more lengthy objective measures of cognitive functioning. Cognitive dysfunction is one of the criteria for the diagnosis of fibromyalgia (FM) and is typically based on self-report questionnaires such as the Symptom Severity Scale.
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